MCM4 (phospho Ser54) rabbit pAb
Product Sizes
50UL
£ POA
ES6207-50UL
100UL
£ POA
ES6207-100UL
About this Product
- SKU:
- ES6207
- Additional Names:
- MCM4; CDC21; DNA replication licensing factor MCM4; CDC21 homolog; P1-CDC21
- Application:
- Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2; 6 and 7 proteins possesses DNA helicase activity; and may act as a DNA unwinding enzyme. The phosphorylation of this protein by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex. This gene is mapped to a region on the chromosome 8 head-to-head next to the PRKDC/DNA-PK; a DNA-activated protein kinase involved in the repair of DNA double-strand breaks. Alternatively spliced transcri
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human MCM4 around the phosphorylation site of Ser54. AA range:20-69
- Isotype:
- IgG
- Reactivities:
- Human, Mouse, Non-human Primate
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
