Lck (phospho Tyr393) rabbit pAb
Product Sizes
50UL
£ POA
ES6094-50UL
100UL
£ POA
ES6094-100UL
About this Product
- SKU:
- ES6094
- Additional Names:
- LCK; Tyrosine-protein kinase Lck; Leukocyte C-terminal Src kinase; LSK; Lymphocyte cell-specific protein-tyrosine kinase; Protein YT16; Proto-oncogene Lck; T cell-specific protein-tyrosine kinase; p56-LCK
- Application:
- Western Blot, Immunofluorescence, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation; a PTK domain; and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs; respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles; and binds to cell surface receptors; including CD4 and CD8; and other signaling molecules. Multiple alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq; Aug 2016];
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human Lck around the phosphorylation site of Tyr393. AA range:361-410
- Isotype:
- IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
