KIR3.1 (phospho Ser185) rabbit pAb
Product Sizes
50UL
£ POA
ES6004-50UL
100UL
£ POA
ES6004-100UL
About this Product
- SKU:
- ES6004
- Additional Names:
- KCNJ3; GIRK1; G protein-activated inward rectifier potassium channel 1; GIRK-1; Inward rectifier K(+) channel Kir3.1; Potassium channel; inwardly rectifying subfamily J member 3
- Application:
- Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Potassium channels are present in most mammalian cells; where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein; which has a greater tendency to allow potassium to flow into a cell rather than out of a cell; is controlled by G-proteins and plays an important role in regulating heartbeat. It associates with three other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex that also couples to neurotransmitter receptors in the brain and whereby channel activation can inhibit action potential firing by hyperpolarizing the plasma membrane. These multimeric G-protein-gated inwardly-rectifying potassium (GIRK) channels may play a role in the pathophysiology of epilepsy; addiction; Down's syndrome; at
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human GIRK1/KIR3.1/KCNJ3 around the phosphorylation site of Ser185. AA range:151-200
- Isotype:
- IgG
- Reactivities:
- Human, Mouse, Rat, Non-human Primate
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
