Hexb rabbit pAb
Product Sizes
50UL
£ POA
ES5730-50UL
100UL
£ POA
ES5730-100UL
About this Product
- SKU:
- ES5730
- Additional Names:
- HEXB; HCC7; Beta-hexosaminidase subunit beta; Beta-N-acetylhexosaminidase subunit beta; Hexosaminidase subunit B; Cervical cancer proto-oncogene 7 protein; HCC-7; N-acetyl-beta-glucosaminidase subunit beta
- Application:
- Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Hexosaminidase B is the beta subunit of the lysosomal enzyme beta-hexosaminidase that; together with the cofactor GM2 activator protein; catalyzes the degradation of the ganglioside GM2; and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits; alpha and beta; which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq; May 2014];
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human HEXB. AA range:481-530
- Isotype:
- IgG
- Reactivities:
- Human, Rat, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
