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Antibodies

BAM32 (phospho Tyr139) rabbit pAb

Product Sizes
50UL
£ POA
ES5538-50UL
100UL
£ POA
ES5538-100UL
About this Product
SKU:
ES5538
Additional Names:
DAPP1; BAM32; HSPC066; Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide; hDAPP1; B lymphocyte adapter protein Bam32; B-cell adapter molecule of 32 kDa
Application:
Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
function:May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K.;induction:Upon B-cell activation.;PTM:Phosphorylated on tyrosine residues.;similarity:Contains 1 PH domain.;similarity:Contains 1 SH2 domain.;subcellular location:Membrane-associated after cell stimulation leading to its translocation.;subunit:Interacts with PtdIns(3;4;5)P3 and PLCG2. In vitro; interacts with PtdIns(3;4)P2.;tissue specificity:Highly expressed in placenta and lung; followed by brain; heart; kidney; liver; pancreas and skeletal muscle. Expressed by B-lymphocytes; but not T-lymphocytes or nonhematopoietic cells.;
Immunogen:
The antiserum was produced against synthesized peptide derived from human DAPP1 around the phosphorylation site of Tyr139. AA range:105-154
Isotype:
IgG
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Type:
Antibodies: Polyclonal Antibody
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