SENP6 rabbit pAb
Product Sizes
50UL
£ POA
ES5463-50UL
100UL
£ POA
ES5463-100UL
About this Product
- SKU:
- ES5463
- Additional Names:
- SENP6; KIAA0797; SSP1; SUSP1; FKSG6; Sentrin-specific protease 6; SUMO-1-specific protease 1; Sentrin/SUMO-specific protease SENP6
- Application:
- Immunohistochemistry, Immunofluorescence, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Ubiquitin-like molecules (UBLs); such as SUMO1 (UBL1; MIM 601912); are structurally related to ubiquitin (MIM 191339) and can be ligated to target proteins in a similar manner as ubiquitin. However; covalent attachment of UBLs does not result in degradation of the modified proteins. SUMO1 modification is implicated in the targeting of RANGAP1 (MIM 602362) to the nuclear pore complex; as well as in stabilization of I-kappa-B-alpha (NFKBIA; MIM 164008) from degradation by the 26S proteasome. Like ubiquitin; UBLs are synthesized as precursor proteins; with 1 or more amino acids following the C-terminal glycine-glycine residues of the mature UBL protein. Thus; the tail sequences of the UBL precursors need to be removed by UBL-specific proteases; such as SENP6; prior to their conjugation to target proteins (Kim et al.; 2000 [PubMed 10799485]). SENPs also display isopeptidase activity for
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human SENP6. AA range:1042-1091
- Isotype:
- IgG
- Reactivities:
- Human, Rat, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
