5-LO (phospho Ser523) rabbit pAb
Product Sizes
50UL
£ POA
ES5390-50UL
100UL
£ POA
ES5390-100UL
About this Product
- SKU:
- ES5390
- Additional Names:
- ALOX5; LOG5; Arachidonate 5-lipoxygenase; 5-LO; 5-lipoxygenase
- Application:
- Western Blot, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein; which is expressed specifically in bone marrow-derived cells; catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8;11;14-cis-eicosatetraenoic acid; and further to the allylic epoxide 5(S)-trans-7;9-trans-11;14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq; Jan 2012];
- Immunogen:
- Synthesized phospho-peptide around the phosphorylation site of human 5-LO (phospho Ser523)
- Isotype:
- IgG
- Reactivities:
- Human, Rat
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
