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Antibodies

SF3b130 rabbit pAb

Product Sizes
50UL
£ POA
ES5345-50UL
100UL
£ POA
ES5345-100UL
About this Product
SKU:
ES5345
Additional Names:
SF3B3; KIAA0017; SAP130; Splicing factor 3B subunit 3; Pre-mRNA-splicing factor SF3b 130 kDa subunit; SF3b130; STAF130; Spliceosome-associated protein 130; SAP 130
Application:
Western Blot, ELISA, Immunohistochemistry
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b; together with splicing factor 3a and a 12S RNA unit; forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex; and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification; transcription; splicing; and DNA repair. [provided by RefSeq; Jul 2008];
Immunogen:
The antiserum was produced against synthesized peptide derived from human SF3B3. AA range:231-280
Isotype:
IgG
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Supplier:
ELK Biotechnology
Type:
Antibodies: Polyclonal Antibody
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