JMJD2B rabbit pAb
Product Sizes
50UL
£ POA
ES5294-50UL
100UL
£ POA
ES5294-100UL
About this Product
- SKU:
- ES5294
- Additional Names:
- KDM4B; JHDM3B; JMJD2B; KIAA0876; Lysine-specific demethylase 4B; JmjC domain-containing histone demethylation protein 3B; Jumonji domain-containing protein 2B
- Application:
- Immunohistochemistry, Immunofluorescence, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- cofactor:Binds 1 Fe(2+) ion per subunit.;domain:The 2 Tudor domains recognize and bind methylated histones. Double Tudor domain has an interdigitated structure and the unusual fold is required for its ability to bind methylated histone tails.;function:Histone demethylase that specifically demethylates 'Lys-9' of histone H3; thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4'; H3 'Lys-27'; H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9'; with a weaker activity than KDM4A; KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.;similarity:Belongs to the JHDM3 histone demethylase family.;similarity:Contains 1 JmjC domain.;similarity:Contains 1 JmjN domain.;similarity:Contains 2 PHD-type zinc fingers.;similarity:Contains 2 Tudor domains.;
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human KDM4B. AA range:351-400
- Isotype:
- IgG
- Reactivities:
- Human, Rat, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
