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Antibodies

FGFR-4 (phospho Tyr642) rabbit pAb

Product Sizes
50UL
£ POA
ES5251-50UL
100UL
£ POA
ES5251-100UL
About this Product
SKU:
ES5251
Additional Names:
FGFR4; JTK2; TKF; Fibroblast growth factor receptor 4; FGFR-4; CD antigen CD334
Application:
Western Blot, ELISA
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
The protein encoded by this gene is a member of the fibroblast growth factor receptor family; where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region; composed of three immunoglobulin-like domains; a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors; setting in motion a cascade of downstream signals; ultimately influencing mitogenesis and differentiation. The genomic organization of this gene; compared to members 1-3; encompasses 18 exons rather than 19 or 20. Although alternative splicing has been observed; there is no evidence that the C-terminal half of the IgII
Immunogen:
Synthesized phospho-peptide around the phosphorylation site of human FGFR-4 (phospho Tyr642)
Isotype:
IgG
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Supplier:
ELK Biotechnology
Type:
Antibodies: Polyclonal Antibody
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