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Antibodies

FGFR-3 rabbit pAb

Product Sizes
50UL
£ POA
ES5249-50UL
100UL
£ POA
ES5249-100UL
About this Product
SKU:
ES5249
Additional Names:
FGFR3; JTK4; Fibroblast growth factor receptor 3; FGFR-3; CD antigen CD333
Application:
Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
This gene encodes a member of the fibroblast growth factor receptor (FGFR) family; with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region; composed of three immunoglobulin-like domains; a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors; setting in motion a cascade of downstream signals; ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dys
Immunogen:
The antiserum was produced against synthesized peptide derived from human FGFR3. AA range:131-180
Isotype:
IgG
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Supplier:
ELK Biotechnology
Type:
Antibodies: Polyclonal Antibody
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