DCC rabbit pAb
Product Sizes
50UL
£ POA
ES4972-50UL
100UL
£ POA
ES4972-100UL
About this Product
- SKU:
- ES4972
- Additional Names:
- DCC; IGDCC1; Netrin receptor DCC; Colorectal cancer suppressor; Immunoglobulin superfamily DCC subclass member 1; Tumor suppressor protein DCC
- Application:
- Western Blot, Immunofluorescence, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules; and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK; also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts; and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor; and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma. [provided by RefSeq; Oct 2009];
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human DCC. AA range:441-490
- Isotype:
- IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
