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Antibodies

COMT rabbit pAb

Product Sizes
50UL
£ POA
ES4761-50UL
100UL
£ POA
ES4761-100UL
About this Product
SKU:
ES4761
Additional Names:
COMT; Catechol O-methyltransferase
Application:
Western Blot, ELISA
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines; including the neurotransmitters dopamine; epinephrine; and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances; COMT is important in the metabolism of catechol drugs used in the treatment of hypertension; asthma; and Parkinson disease. COMT is found in two forms in tissues; a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters. [provided by RefSeq; Sep 2008];
Immunogen:
The antiserum was produced against synthesized peptide derived from human COMT. AA range:61-110
Isotype:
IgG
Reactivities:
Human, Rat, Mouse
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Supplier:
ELK Biotechnology
Type:
Antibodies: Polyclonal Antibody
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