COL6A3 rabbit pAb
Product Sizes
50UL
£ POA
ES4748-50UL
100UL
£ POA
ES4748-100UL
About this Product
- SKU:
- ES4748
- Additional Names:
- COL6A3; Collagen alpha-3(VI) chain
- Application:
- Immunohistochemistry, Immunofluorescence, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes the alpha-3 chain; one of the three alpha chains of type VI collagen; a beaded filament collagen found in most connective tissues. The alpha-3 chain of type VI collagen is much larger than the alpha-1 and -2 chains. This difference in size is largely due to an increase in the number of subdomains; similar to von Willebrand Factor type A domains; that are found in the amino terminal globular domain of all the alpha chains. These domains have been shown to bind extracellular matrix proteins; an interaction that explains the importance of this collagen in organizing matrix components. Mutations in the type VI collagen genes are associated with Bethlem myopathy; a rare autosomal dominant proximal myopathy with early childhood onset. Mutations in this gene are also a cause of Ullrich congenital muscular dystrophy; also referred to as Ullrich scleroatonic muscular dystrophy; an a
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human Collagen VI alpha3. AA range:2261-2310
- Isotype:
- IgG
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
