Calpain 10 rabbit pAb
Product Sizes
50UL
£ POA
ES4603-50UL
100UL
£ POA
ES4603-100UL
About this Product
- SKU:
- ES4603
- Additional Names:
- CAPN10; KIAA1845; Calpain-10; Calcium-activated neutral proteinase 10; CANP 10
- Application:
- Western Blot, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Calpains represent a ubiquitous; well-conserved family of calcium-dependent cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large catalytic subunit has four domains: domain I; the N-terminal regulatory domain that is processed upon calpain activation; domain II; the protease domain; domain III; a linker domain of unknown function; and domain IV; the calmodulin-like calcium-binding domain. This gene encodes a large subunit. It is an atypical calpain in that it lacks the calmodulin-like calcium-binding domain and instead has a divergent C-terminal domain. It is similar in organization to calpains 5 and 6. This gene is associated with type 2 or non-insulin-dependent diabetes mellitus (NIDDM); and is located within the NIDDM1 region. Multiple alternative transcript variants have been described for this gene. [provided by RefSeq;
- Immunogen:
- Synthesized peptide derived from the N-terminal region of human Calpain 10.
- Isotype:
- IgG
- Reactivities:
- Human, Rat, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Type:
- Antibodies: Polyclonal Antibody
