IREβ rabbit pAb
Product Sizes
50UL
£ POA
ES4513-50UL
100UL
£ POA
ES4513-100UL
About this Product
- SKU:
- ES4513
- Additional Names:
- ERN2; IRE2; Serine/threonine-protein kinase/endoribonuclease IRE2; Endoplasmic reticulum-to-nucleus signaling 2; Inositol-requiring protein 2; hIRE2p; Ire1-beta; IRE1b
- Application:
- Immunohistochemistry, Immunofluorescence, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- catalytic activity:ATP + a protein = ADP + a phosphoprotein.;cofactor:Magnesium.;enzyme regulation:The kinase domain is activated by trans-autophosphorylation. Kinase activity is required for activation of the endoribonuclease domain.;function:Induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. Pro-apoptotic. Appears to play no role in the unfolded-protein response; unlike closely related proteins.;PTM:Autophosphorylated.;similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.;similarity:Contains 1 KEN domain.;similarity:Contains 1 protein kinase domain.;
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human ERN2. AA range:841-890
- Isotype:
- IgG
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
