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Antibodies

CRMP-3 rabbit pAb

Product Sizes
50UL
£ POA
ES4508-50UL
100UL
£ POA
ES4508-100UL
About this Product
SKU:
ES4508
Additional Names:
DPYSL4; CRMP3; ULIP4; Dihydropyrimidinase-related protein 4; DRP-4; Collapsin response mediator protein 3; CRMP-3; UNC33-like phosphoprotein 4; ULIP-4
Application:
Western Blot, ELISA
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
disease:Antibodies against post-translationally modified DPYSL4; also called anti-CV2 autoantibodies; are present in sera from patients with paraneoplastic neurological diseases (PND). PND are disorders of the nervous system associated with various systemic cancers which are not a direct result of the tumor mass or metastasis; but attributed to remote effects of the cancer.;function:Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance; neuronal growth cone collapse and cell migration.;PTM:Phosphorylated upon DNA damage; probably by ATM or ATR.;similarity:Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.;subunit:Homotetramer; and heterotetramer with CRMP1; DPYSL2; DPYSL3 or DPYSL5. Interacts with PLEXA1.;
Immunogen:
The antiserum was produced against synthesized peptide derived from human DPYSL4. AA range:91-140
Isotype:
IgG
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Supplier:
ELK Biotechnology
Type:
Antibodies: Polyclonal Antibody
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