IL-12Rβ1 rabbit pAb
Product Sizes
50UL
£ POA
ES4344-50UL
100UL
£ POA
ES4344-100UL
About this Product
- SKU:
- ES4344
- Additional Names:
- IL12RB1; IL12R; IL12RB; Interleukin-12 receptor subunit beta-1; IL-12 receptor subunit beta-1; IL-12R subunit beta-1; IL-12R-beta-1; IL-12RB1; IL-12 receptor beta component; CD212
- Application:
- Western Blot, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- interleukin 12 receptor subunit beta 1(IL12RB1) Homo sapiens The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity; and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer; which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. Mutations in this gene impair the development of interleukin-17-producing T lymphocytes and result in increased susceptibility to mycobacterial and Salmonella infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq; Feb 2014];
- Immunogen:
- The antiserum was produced against synthesized peptide derived from the Internal region of human IL12RB1. AA range:211-260
- Isotype:
- IgG
- Reactivities:
- Human, Rat, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
