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Antibodies

GHR rabbit pAb

Product Sizes
50UL
£ POA
ES4303-50UL
100UL
£ POA
ES4303-100UL
About this Product
SKU:
ES4303
Additional Names:
GHR; Growth hormone receptor; GH receptor; Somatotropin receptor
Application:
Western Blot, ELISA
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
This gene encodes a member of the type I cytokine receptor family; which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome; also known as the growth hormone insensitivity syndrome (GHIS); a disorder characterized by short stature. In humans and rabbits; but not rodents; growth hormone binding protein (GHBP) is generated by proteolytic cleavage of the extracellular ligand-binding domain from the mature growth hormone receptor protein. Multiple alternatively spliced transcript variants have been found for this gene.[provided by RefSeq; Jun 2011];
Immunogen:
The antiserum was produced against synthesized peptide derived from the N-terminal region of human GHR. AA range:21-70
Isotype:
IgG
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Supplier:
ELK Biotechnology
Type:
Antibodies: Polyclonal Antibody
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