Apaf-1 rabbit pAb
Product Sizes
50UL
£ POA
ES4108-50UL
100UL
£ POA
ES4108-100UL
About this Product
- SKU:
- ES4108
- Additional Names:
- APAF1; KIAA0413; Apoptotic protease-activating factor 1; APAF-1
- Application:
- Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain; a caspase recruitment domain (CARD); and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP; this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein; releasing its mature; activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq; Jul 2008];
- Immunogen:
- The antiserum was produced against synthesized peptide derived from the Internal region of human APAF1. AA range:501-550
- Isotype:
- IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
