CD59 rabbit pAb
Product Sizes
50UL
£ POA
ES3982-50UL
100UL
£ POA
ES3982-100UL
About this Product
- SKU:
- ES3982
- Additional Names:
- CD59; MIC11; MIN1; MIN2; MIN3; MSK21; CD59 glycoprotein; 1F5 antigen; 20 kDa homologous restriction factor; HRF-20; HRF20; MAC-inhibitory protein; MAC-IP;MEM43 antigen; Membrane attack complex inhibition factor; MACIF; Membrane inhibitor of reactive lysis; MIRL; Protectin; CD59
- Application:
- Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis; and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex; whereby it binds complement C8 and/or C9 during the assembly of this complex; thereby inhibiting the incorporation of multiple copies of C9 into the complex; which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency; a disease resulting in hemolytic anemia and thrombosis; and which causes cerebral infarction. Multiple alternatively spliced transcript variants; which encode the same protein; have been identified for this gene. [provided by RefSeq; Jul 2008];
- Immunogen:
- The antiserum was produced against synthesized peptide derived from the Internal region of human CD59. AA range:51-100
- Isotype:
- IgG
- Reactivities:
- Human, Rat, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
