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Antibodies

HEXA rabbit pAb

Product Sizes
50UL
£ POA
ES3963-50UL
100UL
£ POA
ES3963-100UL
About this Product
SKU:
ES3963
Additional Names:
HEXA; Beta-hexosaminidase subunit alpha; Beta-N-acetylhexosaminidase subunit alpha; Hexosaminidase subunit A; N-acetyl-beta-glucosaminidase subunit alpha
Application:
Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
This gene encodes a member of the glycosyl hydrolase 20 family of proteins. The encoded preproprotein is proteolytically processed to generate the alpha subunit of the lysosomal enzyme beta-hexosaminidase. This enzyme; together with the cofactor GM2 activator protein; catalyzes the degradation of the ganglioside GM2; and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene lead to an accumulation of GM2 ganglioside in neurons; the underlying cause of neurodegenerative disorders termed the GM2 gangliosidoses; including Tay-Sachs disease (GM2-gangliosidosis type I). Alternative splicing results in multiple transcript variants; at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq; Jan 2016];
Immunogen:
Synthesized peptide derived from HEXA . at AA range: 121-170
Isotype:
IgG
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Supplier:
ELK Biotechnology
Type:
Antibodies: Polyclonal Antibody
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