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Antibodies

LXRα rabbit pAb

Product Sizes
50UL
£ POA
ES3873-50UL
100UL
£ POA
ES3873-100UL
About this Product
SKU:
ES3873
Additional Names:
NR1H3; LXRA; Oxysterols receptor LXR-alpha; Liver X receptor alpha; Nuclear receptor subfamily 1 group H member 3
Application:
Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function; controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs; including liver; kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR); and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq; Oct 2011];
Immunogen:
The antiserum was produced against synthesized peptide derived from the Internal region of human NR1H3. AA range:151-200
Isotype:
IgG
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Supplier:
ELK Biotechnology
Type:
Antibodies: Polyclonal Antibody
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