NCX1 rabbit pAb
Product Sizes
50UL
£ POA
ES3833-50UL
100UL
£ POA
ES3833-100UL
About this Product
- SKU:
- ES3833
- Additional Names:
- SLC8A1; CNC; NCX1; Sodium/calcium exchanger 1; Na(+)/Ca(2+)-exchange protein 1
- Application:
- Western Blot, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- In cardiac myocytes; Ca(2+) concentrations alternate between high levels during contraction and low levels during relaxation. The increase in Ca(2+) concentration during contraction is primarily due to release of Ca(2+) from intracellular stores. However; some Ca(2+) also enters the cell through the sarcolemma (plasma membrane). During relaxation; Ca(2+) is sequestered within the intracellular stores. To prevent overloading of intracellular stores; the Ca(2+) that entered across the sarcolemma must be extruded from the cell. The Na(+)-Ca(2+) exchanger is the primary mechanism by which the Ca(2+) is extruded from the cell during relaxation. In the heart; the exchanger may play a key role in digitalis action. The exchanger is the dominant mechanism in returning the cardiac myocyte to its resting state following excitation.[supplied by OMIM; Apr 2004];
- Immunogen:
- Synthesized peptide derived from NCX1 . at AA range: 270-350
- Isotype:
- IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
