PAOX rabbit pAb
Product Sizes
50UL
£ POA
ES3828-50UL
100UL
£ POA
ES3828-100UL
About this Product
- SKU:
- ES3828
- Additional Names:
- PAOX; PAO; Peroxisomal N(1)-acetyl-spermine/spermidine oxidase; Polyamine oxidase
- Application:
- Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- catalytic activity:N(1);N(12)-diacetylspermine + O(2) + H(2)O = N(1)-acetylspermidine + 3-acetamidobutanal + H(2)O(2).;catalytic activity:N(1)-acetylspermidine + O(2) + H(2)O = putrescine + 3-acetamidopropanal + H(2)O(2).;catalytic activity:N(1)-acetylspermine + O(2) + H(2)O = spermidine + 3-acetamidopropanal + H(2)O(2).;cofactor:Binds 1 FAD per subunit.;function:Flavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)-acetylspermidine > N(1);N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs.;induction:By polyamine analogs.;miscellaneous:Oxidizes N(1)-acetylated polyamines on the exo-side of their N(4)-amino groups. Plant PAO oxidizes spermine on the endo-side of the N(4)-nitrogen.;pathway:Amine and polyamine metabolism; spermine metabolism.;similarity:Belongs to the flavin monoamine oxidase family.;subunit:Monomer.;tissue specificity:Widely expressed. Not detected in spleen. Expressed at lower level in neoplastic tissues.;
- Immunogen:
- Synthesized peptide derived from PAOX . at AA range: 260-340
- Isotype:
- IgG
- Reactivities:
- Human, Rat, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
