NPRL2 rabbit pAb
Product Sizes
50UL
£ POA
ES3816-50UL
100UL
£ POA
ES3816-100UL
About this Product
- SKU:
- ES3816
- Additional Names:
- NPRL2; TUSC4; Nitrogen permease regulator 2-like protein; NPR2-like protein; Gene 21 protein; G21 protein; Tumor suppressor candidate 4
- Application:
- Western Blot, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- function:Suppresses Src-dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling. Down-regulates PDPK1 kinase activity by interfering with tyrosine phosphorylation at the Tyr-9 Tyr-373 and Tyr-376 residues. May act as a tumor suppressor. Suppresses cell growth and enhanced sensitivity to various anticancer drugs.;similarity:Belongs to the NPR2 family.;subunit:Interacts with PDPK1.;tissue specificity:Most abundant in skeletal muscle; followed by brain; liver and pancreas; with lower amounts in lung; kidney; placenta and heart. Expressed in most lung cancer cell lines tested.;
- Immunogen:
- Synthesized peptide derived from the C-terminal region of human NPRL2.
- Isotype:
- IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
