SOCS-1 rabbit pAb
Product Sizes
50UL
£ POA
ES3476-50UL
100UL
£ POA
ES3476-100UL
About this Product
- SKU:
- ES3476
- Additional Names:
- SOCS1; SSI1; TIP3; Suppressor of cytokine signaling 1; SOCS-1; JAK-binding protein; JAB; STAT-induced STAT inhibitor 1; SSI-1; Tec-interacting protein 3; TIP-3
- Application:
- Immunofluorescence, Western Blot, Immunohistochemistry, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes a member of the STAT-induced STAT inhibitor (SSI); also known as suppressor of cytokine signaling (SOCS); family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines; including IL2; IL3 erythropoietin (EPO); CSF2/GM-CSF; and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors; and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action; which is required for normal postnatal growth and survival. [provided by RefSeq; Jul 2008];
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human SOCS-1. AA range:49-98
- Isotype:
- IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Type:
- Antibodies: Polyclonal Antibody
