Smad1/5/9 rabbit pAb
Product Sizes
50UL
£ POA
ES3456-50UL
100UL
£ POA
ES3456-100UL
About this Product
- SKU:
- ES3456
- Additional Names:
- SMAD1; BSP1; MADH1; MADR1; Mothers against decapentaplegic homolog 1; MAD homolog 1; Mothers against DPP homolog 1; JV4-1; Mad-related protein 1; SMAD family member 1; SMAD 1; Smad1; hSMAD1; Transforming growth factor-beta-signaling protein
- Application:
- Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The protein encoded by this gene belongs to the SMAD; a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs); which are involved in a range of biological activities including cell growth; apoptosis; morphogenesis; development and immune responses. In response to BMP ligands; this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4; which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases; such as SMURF1 and SMURF2; and undergoes ubiquitination and proteasome-med
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human Smad1/5/9. AA range:10-59
- Isotype:
- IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Type:
- Antibodies: Polyclonal Antibody
