SEMA4A rabbit pAb
Product Sizes
50UL
£ POA
ES3418-50UL
100UL
£ POA
ES3418-100UL
About this Product
- SKU:
- ES3418
- Additional Names:
- SEMA4A; SEMAB; SEMB; Semaphorin-4A; Semaphorin-B; Sema B
- Application:
- Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes a member of the semaphorin family of soluble and transmembrane proteins. Semaphorins are involved in numerous functions; including axon guidance; morphogenesis; carcinogenesis; and immunomodulation. The encoded protein is a single-pass type I membrane protein containing an immunoglobulin-like C2-type domain; a PSI domain and a sema domain. It inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. It is an activator of T-cell-mediated immunity and suppresses vascular endothelial growth factor (VEGF)-mediated endothelial cell migration and proliferation in vitro and angiogenesis in vivo. Mutations in this gene are associated with retinal degenerative diseases including retinitis pigmentosa type 35 (RP35) and cone-rod dystrophy type 10 (CORD10). Multiple alternatively spliced transcript variants encoding different isoforms have been identif
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human SEMA4A. AA range:501-550
- Isotype:
- IgG
- Reactivities:
- Human, Mouse, Rat, Non-human Primate
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
