Rock-1 rabbit pAb
Product Sizes
50UL
£ POA
ES3387-50UL
100UL
£ POA
ES3387-100UL
About this Product
- SKU:
- ES3387
- Additional Names:
- ROCK1; Rho-associated protein kinase 1; Renal carcinoma antigen NY-REN-35; Rho-associated; coiled-coil-containing protein kinase 1; Rho-associated; coiled-coil-containing protein kinase I; ROCK-I; p160 ROCK-1; p160ROCK
- Application:
- Immunofluorescence, Western Blot, Immunohistochemistry, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts; as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein; a downstream effector of Rho; phosphorylates and activates LIM kinase; which in turn; phosphorylates cofilin; inhibiting its actin-depolymerizing activity. A pseudogene; related to this gene; is also located on chromosome 18. [provided by RefSeq; Aug 2015];
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human Rock-1. AA range:262-311
- Isotype:
- IgG
- Reactivities:
- Human, Mouse, Rat, Non-human Primate
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
