M-RIP rabbit pAb
Product Sizes
50UL
£ POA
ES3382-50UL
100UL
£ POA
ES3382-100UL
About this Product
- SKU:
- ES3382
- Additional Names:
- MPRIP; KIAA0864; MRIP; RHOIP3; Myosin phosphatase Rho-interacting protein; M-RIP; Rho-interacting protein 3; RIP3; p116Rip
- Application:
- Western Blot, ELISA, Immunohistochemistry
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- function:Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells.;similarity:Contains 1 PH domain.;similarity:Contains 2 PH domains.;subcellular location:Colocalizes with F-actin.;subunit:Binds F-actin through its N-terminus (By similarity). Binds RHOA; PPP1R12A/MBS and PPP1R12C/MBS85 through adjacent coiled coil domains.;
- Immunogen:
- Synthesized peptide derived from the Internal region of human M-RIP.
- Isotype:
- IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
