Rap1GAP rabbit pAb
Product Sizes
50UL
£ POA
ES3327-50UL
100UL
£ POA
ES3327-100UL
About this Product
- SKU:
- ES3327
- Additional Names:
- RAP1GAP; KIAA0474; RAP1GA1; Rap1 GTPase-activating protein 1; Rap1GAP; Rap1GAP1
- Application:
- Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- RAP1 GTPase activating protein(RAP1GAP) Homo sapiens This gene encodes a type of GTPase-activating-protein (GAP) that down-regulates the activity of the ras-related RAP1 protein. RAP1 acts as a molecular switch by cycling between an inactive GDP-bound form and an active GTP-bound form. The product of this gene; RAP1GAP; promotes the hydrolysis of bound GTP and hence returns RAP1 to the inactive state whereas other proteins; guanine nucleotide exchange factors (GEFs); act as RAP1 activators by facilitating the conversion of RAP1 from the GDP- to the GTP-bound form. In general; ras subfamily proteins; such as RAP1; play key roles in receptor-linked signaling pathways that control cell growth and differentiation. RAP1 plays a role in diverse processes such as cell proliferation; adhesion; differentiation; and embryogenesis. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq; Aug 2011];
- Immunogen:
- Synthesized peptide derived from Rap1GAP . at AA range: 460-540
- Isotype:
- IgG
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
