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Antibodies

Rad50 rabbit pAb

Product Sizes
50UL
£ POA
ES3306-50UL
100UL
£ POA
ES3306-100UL
About this Product
SKU:
ES3306
Additional Names:
RAD50; DNA repair protein RAD50; hRAD50
Application:
Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
RAD50 double strand break repair protein(RAD50) Homo sapiens The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50; a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein; cooperating with its partners; is important for DNA double-strand break repair; cell cycle checkpoint activation; telomere maintenance; and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.[provided by RefSeq; Apr 2010];
Immunogen:
The antiserum was produced against synthesized peptide derived from human RAD50. AA range:681-730
Isotype:
IgG
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Supplier:
ELK Biotechnology
Type:
Antibodies: Polyclonal Antibody
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