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Antibodies

PLC γ1 rabbit pAb

Product Sizes
50UL
£ POA
ES3235-50UL
100UL
£ POA
ES3235-100UL
About this Product
SKU:
ES3235
Additional Names:
PLCG1; PLC1; 1-phosphatidylinositol 4; 5-bisphosphate phosphodiesterase gamma-1; PLC-148; Phosphoinositide phospholipase C-gamma-1; Phospholipase C-II; PLC-II; Phospholipase C-gamma-1; PLC-gamma-1
Application:
Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
The protein encoded by this gene catalyzes the formation of inositol 1;4;5-trisphosphate and diacylglycerol from phosphatidylinositol 4;5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example; when activated by SRC; the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi; where it activates Ras. Also; this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq; Jul 2008];
Immunogen:
The antiserum was produced against synthesized peptide derived from human PLCG1. AA range:736-785
Isotype:
IgG
Reactivities:
Human, Mouse, Rat, Non-human Primate
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Supplier:
ELK Biotechnology
Type:
Antibodies: Polyclonal Antibody
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