MLKL rabbit pAb
Product Sizes
50UL
£ POA
ES2800-50UL
100UL
£ POA
ES2800-100UL
About this Product
- SKU:
- ES2800
- Additional Names:
- MLKL; Mixed lineage kinase domain-like protein
- Application:
- Western Blot, Immunohistochemistry
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain; however; is thought to be inactive because it lacks several residues required for activity. This protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis; a programmed cell death process; via interaction with receptor-interacting protein 3 (RIP3); which is a key signaling molecule in necroptosis pathway. Inhibitor studies and knockdown of this gene inhibited TNF-induced necrosis. High levels of this protein and RIP3 are associated with inflammatory bowel disease in children. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq; Sep 2015];
- Immunogen:
- Synthesized peptide derived from MLKL . at AA range: 40-120
- Isotype:
- IgG
- Reactivities:
- Human, Rat, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
