MGMT rabbit pAb
Product Sizes
50UL
£ POA
ES2788-50UL
100UL
£ POA
ES2788-100UL
About this Product
- SKU:
- ES2788
- Additional Names:
- MGMT; Methylated-DNA--protein-cysteine methyltransferase; 6-O-methylguanine-DNA methyltransferase; MGMT; O-6-methylguanine-DNA-alkyltransferase
- Application:
- Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Alkylating agents are potent carcinogens that can result in cell death; mutation and cancer. The protein encoded by this gene is a DNA repair protein that is involved in cellular defense against mutagenesis and toxicity from alkylating agents. The protein catalyzes transfer of methyl groups from O(6)-alkylguanine and other methylated moieties of the DNA to its own molecule; which repairs the toxic lesions. Methylation of the genes promoter has been associated with several cancer types; including colorectal cancer; lung cancer; lymphoma and glioblastoma. [provided by RefSeq; Sep 2015];
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human MGMT. AA range:1-50
- Isotype:
- IgG
- Reactivities:
- Human, Rat
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
