Melanopsin rabbit pAb
Product Sizes
50UL
£ POA
ES2777-50UL
100UL
£ POA
ES2777-100UL
About this Product
- SKU:
- ES2777
- Additional Names:
- OPN4; MOP; Melanopsin; Opsin-4
- Application:
- Western Blot, ELISA, Immunohistochemistry
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. This gene encodes a photoreceptive opsin protein that is expressed within the ganglion and amacrine cell layers of the retina. In mouse; retinal ganglion cell axons expressing this gene projected to the suprachiasmatic nucleus and other brain nuclei involved in circadian photoentrainment. In mouse; this protein is coupled to a transient receptor potential (TRP) ion channel through a G protein signaling pathway and produces a physiologic light response via membrane depolarization and increased intracellular calcium. The protein functions as a sensory photopigment and may also have photoisomerase activity. Experiments with knockout mice indicate that this gene attenuates; but does not abolish; photoentrainment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by Ref
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human OPN4. AA range:429-478
- Isotype:
- IgG
- Reactivities:
- Human, Rat, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
