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Antibodies

MDA5 rabbit pAb

Product Sizes
50UL
£ POA
ES2762-50UL
100UL
£ POA
ES2762-100UL
About this Product
SKU:
ES2762
Additional Names:
IFIH1; MDA5; RH116; Interferon-induced helicase C domain-containing protein 1; Clinically amyopathic dermatomyositis autoantigen 140 kDa; CADM-140 autoantigen; Helicase with 2 CARD domains; Helicard; Interferon-induced with helicase C domai
Application:
Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
DEAD box proteins; characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD); are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation; nuclear and mitochondrial splicing; and ribosome and spliceosome assembly. Based on their distribution patterns; some members of this family are believed to be involved in embryogenesis; spermatogenesis; and cellular growth and division. This gene encodes a DEAD box protein that is upregulated in response to treatment with beta-interferon and a protein kinase C-activating compound; mezerein. Irreversible reprogramming of melanomas can be achieved by treatment with both these agents; treatment with either agent alone only achieves reversible differentiation. Genetic variation in this gene is associated with diabetes mellitus insulin-depend
Immunogen:
The antiserum was produced against synthesized peptide derived from human IFIH1. AA range:976-1025
Isotype:
IgG
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Supplier:
ELK Biotechnology
Type:
Antibodies: Polyclonal Antibody
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