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Antibodies

IgA rabbit pAb

Product Sizes
50UL
£ POA
ES2594-50UL
100UL
£ POA
ES2594-100UL
About this Product
SKU:
ES2594
Additional Names:
IGHA1; Ig alpha-1 chain C region; IGHA2; Ig alpha-2 chain C region
Application:
Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
disease:A chromosomal aberration involving IGHA1 is found in multiple myeloma (MM) cell lines. Translocation t(1;14)(q21;q32) that forms a FCRL4-IGHA1 fusion protein.;function:Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system.;PTM:3-Hydroxykynurenine; an oxidized tryptophan metabolite that is common in biological fluids; reacts with alpha-1-microglobulin to form heterogeneous polycyclic chromophores including hydroxanthommatin. The chromophore reacts with accessible cysteines forming non-reducible thioether cross-links with Ig alpha-1 chain C region Cys-352.;similarity:Contains 3 Ig-like (immunoglobulin-like) domains.;subunit:Monomeric or polymeric.;
Immunogen:
The antiserum was produced against synthesized peptide derived from human IgA. AA range:227-276
Isotype:
IgG
Reactivities:
Human, Rat, Mouse
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Supplier:
ELK Biotechnology
Type:
Antibodies: Polyclonal Antibody
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