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Antibodies

HLA-DOβ rabbit pAb

Product Sizes
50UL
£ POA
ES2537-50UL
100UL
£ POA
ES2537-100UL
About this Product
SKU:
ES2537
Additional Names:
HLA-DOB; HLA class II histocompatibility antigen; DO beta chain; MHC class II antigen DOB
Application:
Western Blot, ELISA
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
HLA-DOB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DOA) and a beta chain (DOB); both anchored in the membrane. It is located in intracellular vesicles. DO suppresses peptide loading of MHC class II molecules by inhibiting HLA-DM. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes; dendritic cells; macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide; exons 2 and 3 encode the two extracellular domains; exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. [provided by RefSeq; Jul 2008];
Immunogen:
The antiserum was produced against synthesized peptide derived from human HLA-DOB. AA range:1-50
Isotype:
IgG
Reactivities:
Human
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Supplier:
ELK Biotechnology
Type:
Antibodies: Polyclonal Antibody
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