HBO1 rabbit pAb
Product Sizes
50UL
£ POA
ES2494-50UL
100UL
£ POA
ES2494-100UL
About this Product
- SKU:
- ES2494
- Additional Names:
- KAT7; HBO1; HBOa; MYST2; Histone acetyltransferase KAT7; Histone acetyltransferase binding to ORC1; Lysine acetyltransferase 7; MOZ; YBF2/SAS3; SAS2 and TIP60 protein 2; MYST-2
- Application:
- Western Blot, Immunofluorescence, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- catalytic activity:Acetyl-CoA + histone = CoA + acetylhistone.;domain:The C2HC-type zinc finger is required for interaction with MCM2 and ORC1L.;domain:The N-terminus is involved in transcriptional repression; while the C-terminus mediates AR-interaction.;function:Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity; a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may regulate DNA replication and act as a coactivator of TP53-dependent transcription. Specifically represses AR-mediated transcription.;PTM:Phosphorylated upon DNA damage; probably by ATM or ATR.;similarity:Belongs to the MYST (SAS/MOZ) family.;similarity:Contains 1 C2HC-type zinc finger.;subunit:Component of the HBO1 complex composed at least of ING4 or ING5; MYTS2/HBO1; EAF6; and one of PHF15; PHF16 and PHF17. Interacts with MCM2 and ORC1L. Interacts with the androgen receptor (AR) in the presence of dihydrotestosterone.;tissue specificity:Ubiquitously expressed; with highest levels in testis.;
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human MYST2. AA range:131-180
- Isotype:
- IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
