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Antibodies

GTBP rabbit pAb

Product Sizes
50UL
£ POA
ES2489-50UL
100UL
£ POA
ES2489-100UL
About this Product
SKU:
ES2489
Additional Names:
MSH6; GTBP; DNA mismatch repair protein Msh6; hMSH6; G/T mismatch-binding protein; GTBP; GTMBP; MutS-alpha 160 kDa subunit; p160
Application:
Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
This gene encodes a member of the DNA mismatch repair MutS family. In E. coli; the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa; called the Walker-A adenine nucleotide binding motif; exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer; colorectal cancer; and endometrial cancer. Transcripts variants encoding different isoforms have been described. [provided by RefSeq; Jul 2013];
Immunogen:
The antiserum was produced against synthesized peptide derived from human MSH6. AA range:341-390
Isotype:
IgG
Reactivities:
Human, Mouse, Non-human Primate
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Supplier:
ELK Biotechnology
Type:
Antibodies: Polyclonal Antibody
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