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Antibodies

Ghrelin rabbit pAb

Product Sizes
50UL
£ POA
ES2421-50UL
100UL
£ POA
ES2421-100UL
About this Product
SKU:
ES2421
Additional Names:
GHRL; MTLRP; Appetite-regulating hormone; Growth hormone secretagogue; Growth hormone-releasing peptide; Motilin-related peptide; Protein M46
Application:
Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
This gene encodes the ghrelin-obestatin preproprotein that is cleaved to yield two peptides; ghrelin and obestatin. Ghrelin is a powerful appetite stimulant and plays an important role in energy homeostasis. Its secretion is initiated when the stomach is empty; whereupon it binds to the growth hormone secretagogue receptor in the hypothalamus which results in the secretion of growth hormone (somatotropin). Ghrelin is thought to regulate multiple activities; including hunger; reward perception via the mesolimbic pathway; gastric acid secretion; gastrointestinal motility; and pancreatic glucose-stimulated insulin secretion. It was initially proposed that obestatin plays an opposing role to ghrelin by promoting satiety and thus decreasing food intake; but this action is still debated. Recent reports suggest multiple metabolic roles for obestatin; including regulating adipocyte function
Immunogen:
The antiserum was produced against synthesized peptide derived from human Ghrelin. AA range:47-96
Isotype:
IgG
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Type:
Antibodies: Polyclonal Antibody
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