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Antibodies

Fibulin-5 rabbit pAb

Product Sizes
50UL
£ POA
ES2344-50UL
100UL
£ POA
ES2344-100UL
About this Product
SKU:
ES2344
Additional Names:
FBLN5; DANCE; Fibulin-5; FIBL-5; Developmental arteries and neural crest EGF-like protein; Dance; Urine p50 protein; UP50
Application:
Western Blot, ELISA
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
The protein encoded by this gene is a secreted; extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However; its expression is reinduced in balloon-injured vessels and atherosclerotic lesions; notably in intimal vascular smooth muscle cells and endothelial cells. Therefore; the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa; autosomal recessive cutis laxa type I (CL type I); and age-related macular degeneration type 3 (ARMD3). [provided by RefSeq; Jul 2008];
Immunogen:
The antiserum was produced against synthesized peptide derived from human FBLN5. AA range:171-220
Isotype:
IgG
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Supplier:
ELK Biotechnology
Type:
Antibodies: Polyclonal Antibody
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