ER81 rabbit pAb
Product Sizes
50UL
£ POA
ES2286-50UL
100UL
£ POA
ES2286-100UL
About this Product
- SKU:
- ES2286
- Additional Names:
- ETV1; ER81; ETS translocation variant 1; Ets-related protein 81
- Application:
- Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes a member of the ETS (E twenty-six) family of transcription factors. The ETS proteins regulate many target genes that modulate biological processes like cell growth; angiogenesis; migration; proliferation and differentiation. All ETS proteins contain an ETS DNA-binding domain that binds to DNA sequences containing the consensus 5'-CGGA[AT]-3'. The protein encoded by this gene contains a conserved short acidic transactivation domain (TAD) in the N-terminal region; in addition to the ETS DNA-binding domain in the C-terminal region. This gene is involved in chromosomal translocations; which result in multiple fusion proteins including EWS-ETV1 in Ewing sarcoma and at least 10 ETV1 partners (see PMID: 19657377; Table 1) in prostate cancer. In addition to chromosomal rearrangement; this gene is overexpressed in prostate cancer; melanoma and gastrointestinal stromal tumor. Multiple alte
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human ER81. AA range:10-59
- Isotype:
- IgG
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
