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Antibodies

Dnmt3b rabbit pAb

Product Sizes
50UL
£ POA
ES2189-50UL
100UL
£ POA
ES2189-100UL
About this Product
SKU:
ES2189
Additional Names:
DNMT3B; DNA (cytosine-5)-methyltransferase 3B; Dnmt3b; DNA methyltransferase HsaIIIB; DNA MTase HsaIIIB; M.HsaIIIB
Application:
Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
CpG methylation is an epigenetic modification that is important for embryonic development; imprinting; and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation; rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined. [provided by RefSeq; May 2011];
Immunogen:
The antiserum was produced against synthesized peptide derived from human DNMT3B. AA range:1-50
Isotype:
IgG
Reactivities:
Human
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Supplier:
ELK Biotechnology
Type:
Antibodies: Polyclonal Antibody
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