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Antibodies

DHRS4 rabbit pAb

Product Sizes
50UL
£ POA
ES2170-50UL
100UL
£ POA
ES2170-100UL
About this Product
SKU:
ES2170
Additional Names:
DHRS4; Dehydrogenase/reductase SDR family member 4; NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase; CR; PHCR; NADPH-dependent retinol dehydrogenase/reductase; NRDR; humNRDR; Peroxisomal short-chain alcohol dehydrogenase; PSCD
Application:
Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
catalytic activity:R-CHOH-R' + NADP(+) = R-CO-R' + NADPH.;function:Reduces all-trans-retinal and 9-cis retinal. Can also catalyze the oxidation of all-trans-retinol with NADP as co-factor; but with much lower efficiency. Reduces alkyl phenyl ketones and alpha-dicarbonyl compounds with aromatic rings; such as pyrimidine-4-aldehyde; 3-benzoylpyridine; 4-benzoylpyridine; menadione and 4-hexanoylpyridine. Has no activity towards aliphatic aldehydes and ketones.;miscellaneous:Inhibited by kaempferol; quercetin; genistein and myristic acid.;similarity:Belongs to the short-chain dehydrogenases/reductases (SDR) family.;subcellular location:Isoform 1 is peroxisomal; while isoform 4 is not.;subunit:Homotetramer.;tissue specificity:Isoform 1 is predominantly expressed in normal cervix (at protein level). Isoform 4 is expressed in some neoplastic cervical tissues; but not in normal cervix (at protein level). Isoforms 5 and 6 are expressed in a few neoplastic cervical tissues.;
Immunogen:
The antiserum was produced against synthesized peptide derived from human DHRS4. AA range:191-240
Isotype:
IgG
Reactivities:
Human, Rat, Mouse
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Supplier:
ELK Biotechnology
Type:
Antibodies: Polyclonal Antibody
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