CYP1A1/2 rabbit pAb
Product Sizes
50UL
£ POA
ES2093-50UL
100UL
£ POA
ES2093-100UL
About this Product
- SKU:
- ES2093
- Additional Names:
- CYP1A1; Cytochrome P450 1A1; CYPIA1; Cytochrome P450 form 6; Cytochrome P450-C; Cytochrome P450-P1; CYP1A2; Cytochrome P450 1A2; CYPIA2; Cytochrome P(3)450; Cytochrome P450 4; Cytochrome P450-P3
- Application:
- Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene; CYP1A1; encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol; steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs); some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however; it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member; CYP1A2; is located approximately 25 kb away from CYP1A1 on chromosome 15. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq; Jan 2016];
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human Cytochrome P450 1A1/2. AA range:71-120
- Isotype:
- IgG
- Reactivities:
- Human, Mouse, Rat, Non-human Primate
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
