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Antibodies

AMPKα2 rabbit pAb

Product Sizes
50UL
£ POA
ES20835-50UL
100UL
£ POA
ES20835-100UL
About this Product
SKU:
ES20835
Additional Names:
PRKAA2; AMPK; AMPK2; 5'-AMP-activated protein kinase catalytic subunit alpha-2; AMPK subunit alpha-2; Acetyl-CoA carboxylase kinase; ACACA kinase; Hydroxymethylglutaryl-CoA reductase kinase; HMGCR kinase
Application:
Western Blot
Clonality:
Polyclonal
Extra Details:
The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit; and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses; AMPK is activated; and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR); key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. [provided by RefSeq; Jul 2008];
Immunogen:
Recombinant Protein of AMPKα2
Isotype:
IgG
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Source:
Rabbit
Storage Conditions:
-20[o]C
Supplier:
ELK Biotechnology
Type:
Antibodies: Polyclonal Antibody
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