Glucocorticoid receptor rabbit pAb
Product Sizes
50UL
£ POA
ES20734-50UL
100UL
£ POA
ES20734-100UL
About this Product
- SKU:
- ES20734
- Additional Names:
- NR3C1; GRL; Glucocorticoid receptor; GR; Nuclear receptor subfamily 3 group C member 1
- Application:
- Western Blot
- Clonality:
- Polyclonal
- Extra Details:
- This gene encodes glucocorticoid receptor; which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription; and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm; but upon ligand binding; is transported into the nucleus. It is involved in inflammatory responses; cellular proliferation; and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance. Alternative splicing of this gene results in transcript variants encoding either the same or different isoforms. Additional isoforms resulting from the use of alternate in-frame translation initiation sites have also been described; and shown to be functional; displaying diverse cytoplasm-to-nucleus trafficking pat
- Immunogen:
- Recombinant Protein of Glucocorticoid receptor
- Isotype:
- IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Source:
- Rabbit
- Storage Conditions:
- -20[o]C
- Supplier:
- ELK Biotechnology
- Type:
- Antibodies: Polyclonal Antibody
